Shaping the Future of Toxicology:
Discover VICT3R!
VICT3R (Developing and implementing VIrtual Control groups To reducE animal use in toxicology Research) is a public-private partnership funded by the Innovative Health Initiative (IHI). The project is dedicated to reducing animal use in toxicology research by developing Virtual Control Groups (VCGs) — an innovative approach that enhances scientific outcomes while aligning with the 3Rs principles (Replacement, Reduction, and Refinement). Through this work, VICT3R aims to advance ethical and data-driven alternatives in regulatory testing.
Developing Virtual Control Groups
VICT3R is developing and validating VCGs as a data-driven alternative to traditional control groups. By leveraging historical control data, AI and advanced statistical methods, VCGs can provide a scientifically robust and ethically responsible solution for regulatory assessments.
Public-Private Partnership for Change
VICT3R is a public-private partnership uniting industry leaders, academic institutions, and small and medium-sized enterprises. This collaboration ensures a scientifically rigorous approach to developing VCGs while fostering broad acceptance and implementation across the biomedical and regulatory science sectors.
Data Sharing
VICT3R is building a comprehensive, high-quality database of control animal data provided by the industry, accessible to project partners, regulators, and policymakers worldwide. By harnessing historical toxicology data, the project enhances scientific rigor, improves transparency, and supports better decision-making in regulatory assessments.
Advancing Regulatory Acceptance of VCGs
VICT3R is committed to generating the scientific and regulatory evidence needed to validate VCGs, ensuring their credibility and paving the way for their integration into toxicology research and regulatory frameworks.
Reducing Animal Use
VICT3R aims to reduce animal use in toxicology research by replacing concurrent control groups with Virtual Control Groups (VCGs). This shift has the potential to decrease animal use by up to 25% while maintaining scientific integrity.
